The 24-foot-long reticulated python at the Columbus Zoo and Aquarium died Tuesday night.

The 24-foot-long reticulated python at the Columbus Zoo and Aquarium died Tuesday night.

Fluffy, who came to the zoo in March 2007, died of an apparent tumor. The 18-year-old python weighed 300 pounds and held the Guinness World Record for longest snake.

Fluffy came to the zoo originally on loan, but the new habitat for the snake became its home.

"When zoo visitors saw Fluffy they experienced many emotions such as awe, curiosity and even fear" zoo president and CEO Dale Schmidt said in a news release. "Everyone was moved by her presence and she created the connection for them to learn more, and care more, about misunderstood animals such as snakes."

Preliminary findings of an autopsy performed by the Ohio State University's College of Veterinary Medicine found a mass on Fluffy's ovary.