The contest appears to be a mismatch, as South is averaging 35.7 points per game and North is allowing 41.2.
Nick Renzetti is among the area's passing leaders, having completed 173 of 296 passes for 2,803 yards. His primary targets are Jalen Bell, who has 60 receptions for 960 yards and has scored 13 touchdowns, and Marcus Ball, who has 43 catches for 670 yards.
North, which has lost 44 consecutive games and is 6-63 since the start of the 2006 season, is averaging just 10 points per game and has yet to score more than 14 points. The Warriors have been held to seven points or fewer four times.
South has won the past five meetings. North's last win in the series came in 2005, when it defeated the Wildcats 14-10 en route to a 5-5 record. That season marked the last time the Warriors didn't finish with a losing record.
*Last week: North led Kilbourne 6-0 after the first quarter on a 20-yard fumble return by Nick Perrotti, but the Wolves scored the final 26 points.
The Warriors were held to 159 total yards.
Renzetti led the way for South in its overtime win over Jerome, completing 14 of 26 passes for 300 yards with two touchdowns and three interceptions. He connected with tight end Darryl Long on a 9-yard touchdown pass and with wide receiver Torrodd Carter on a 67-yard scoring pass.
Carter had five receptions for 132 yards and Noah Prentiss rushed for 91 yards and a touchdown on 19 carries.
The game was tied at 13 at the end of regulation and Jerome took a 20-13 lead on its overtime possession. South answered with a 2-yard touchdown run by Prentiss and opted to go for two points instead of attempting the extra point to force a second overtime. Renzetti completed a pass to Carter for the two-point conversion, giving the Wildcats the win.
Jerome running back Donovan Wilson rushed for 424 yards and three touchdowns on 59 carries.