In August 1966, August A. Busch Jr. of brewing giant Anheuser-Busch broke ground for the new brewery in Columbus at 700 Schrock Road.
Shown with four reins in each hand, Busch started the eight Clydesdales hitched to a plow for a formal groundbreaking.
When the plant opened two years later, it was the sixth brewery for the company, with a home plant in St. Louis.
Today, Anheuser-Busch operates 12 breweries -- plus 10 craft breweries -- throughout the United States.
In 1969, a small herd of buffalo and deer arrived for an animal reserve on the Columbus grounds.
A proposed theme park or animal park was never built, however, so in 1974, the herd was relocated to Busch Gardens in Virginia.