St. Louis Cardinals at Chicago Cubs odds, picks and best bets

Tim Heaney
Sportsbook Wire

The St. Louis Cardinals (4-4) and Chicago Cubs (13-6) will play a doubleheader Monday and will squeeze five games into a three-day series at Wrigley Field. We analyze the Cardinals-Cubs MLB betting odds and lines, with picks and best bets.

This article covers betting tips for Game 1 of Monday's doubleheader, which starts at 5:15 p.m. ET and will have the Cubs as the home squad. The Cards will act as the home team in the nightcaps of Monday and Wednesday's twin bills.

Cardinals at Cubs: Projected starting pitchers

LHP Kwang-Hyun Kim at RHP Kyle Hendricks

Kim's 2020 stats: 1 IP, 1 SV

  • Yep, he was the closer in his July 24 MLB debut. Now, he's in the rotation as the Cardinals continue to re-emerge from their COVID-19 quarantine. He probably won't go too deep into this game.

Hendricks' 2020 stats: 3-1, 3.08 ERA, 0.99 WHIP in 4 starts (20:2 K:BB in 26 1/3 IP)

  • Home in 2019: 2.04 ERA, 82:13 in 92 2/3 IP
  • Home in career: 2.56 ERA, 7.80 K/9, 1.80 BB/9

Get some action on this game or any other matchup with an MLB bet at BetMGM in NJ, IN, CO and WV. Bet now!

Cardinals at Cubs: Key injuries

(Get the latest injury news here.)

Cardinals

  • C Yadier Molina (COVID-19) out
  • SS Paul DeJong (COVID-19 list) out
  • RP Ryan Helsley (COVID-19) out
  • RP Austin Gomber (COVID-19 list) out
  • RP Jordan Hicks (elbow/personal) out for season

Cubs

  • OF Jason Heyward (back) questionable

Also see: BaseballHQ Fantasy Baseball

Cardinals at Cubs: Odds, lines, picks and betting tips

MLB odds courtesy of BetMGM; access USA TODAY Sports for a full list. Odds last updated at 11 a..m. ET.

Prediction

Cubs 5, Cardinals 2

The Cardinals just swept the Chicago White Sox over the weekend, but while St. Louis has been quarantined, the Cubs have been rolling, and Hendricks is nearly unstoppable at Wrigley Field.

Moneyline (ML)

  • Cardinals (+155)
  • Cubs (-176)

Bet against Hendricks at home? No thanks. Throw down nearly $2 to make $1? No thanks. PASS.

Run line/Against the spread (ATS)

  • Cardinals +1.5 (-154)
  • Cubs -1.5 (+125)

Avoid the Moneyline and BET CUBS -1.5 (+125). St. Louis visiting Wrigley Field will not work out well for them.

New to sports betting? A winning $10 bet on the Cubs' run line of -1.5 (+125) would return a profit of $12.50.

Over/Under (O/U)

  • Over 6.5 (-110)
  • Under 6.5 (-110)

Sure, BET OVER 6.5 (-110). It's low enough to give you cushion once the bullpens come into play late in the game, though the Cubs probably will carry the weight.

New to sports betting? A winning $10 bet on the Over would return a profit of $9.09.

Want some action on this game? Place a bet at BetMGM now. For more sports betting tips and advice, visit SportsbookWire.com.

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